Long term frequency stability analysis of the GPS NAVSTAR 6 Cesium clock

Time domain measurements, taken between the NAVSTAR 6 Spacecraft Vehicle (SV) and the Vandenberg Global Positioning System (GPS) Monitor Site, by a pseudo random noise receiver, were collected over an extended period of time and analyzed to estimate the long term frequency stability of the NAVSTAR 6 onboard frequency standard, referenced to the Vandenberg MS frequency standard. The technique employed separates the clock offset from the composite signal by first applying corrections for equipment delays, ionospheric delay, tropospheric delay, Earth rotation and the relativistic effect. The data are edited and smoothed using the predicted SV ephemeris to calculate the geometric delay. Then all available passes from each of the four GPS monitor stations, are collected at 1-week intervals and used to calculate the NAVSTAR orbital elements. The procedure is then completed by subtracting the corrections and the geometric delay, using the final orbital elements, from the composite signal, thus leaving the clock offset and random error

Host race evolution in the pyralid moth Dicymolomia Julianalis (Walker) on selected hosts in Tennessee

Dicymolomia julianalis (Walker) (Lepidoptera: Pyralidae) has a diverse feeding habitats, which range from herbivore to scavenger to predator. Allozyme analysis of fourteen loci was used to evaluate if populations of D. julianalis sampled from cat-tail, musk thistle, and common bagworm are genetically differentiated. Significant heterogeneity in allele frequencies exists at eight of nine loci examined. Analyses of population structure indicate that host is more important than geographic location in explaining the distribution of variation. Estimates of migration indicate that a restriction in gene flow exists among populations of D. julianalis. Genetic distances indicate that musk thistle and bagworm populations are more similar to each other than both are to cat-tail populations. The phenogram produced by UPGMA of Modified Rogers genetic distances indicate that two fairly separated groups exist in D. julianalis. The first group contains only cat-tail populations and the second musk thistle and common bagworm populations. The phenetic analysis indicates that the musk thistle race was most recently derived from the common bagworm race. Results of allozyme analysis indicate that populations of D. julianalis are genetically differentiated on these three hosts. As such, host race formation as the first step in sympatric speciation appears to be important in this species

Submicrosecond comparisons of time standards via the Navigation Technology Satellites (NTS)

An interim demonstration was performed of the time transfer capability of the NAVSTAR GPS system using a single NTS satellite. Measurements of time difference (pseudo-range) are made from the NTS tracking network and at the participating observatories. The NTS network measurements are used to compute the NTS orbit trajectory. The central NTS tracking station has a time link to the Naval Observatory UTC (USNO,MC1) master clock. Measurements are used with the NTS receiver at the remote observatory, the time transfer value UTC (USNO,MC1)-UTC (REMOTE, VIA NTS) is calculated. Intercomparisons were computed using predicted values of satellite clock offset and ephemeus

Submicrosecond comparison of international clock synchronization by VLBI and the NTS satellite

The intercontinental clock synchronization capabilities of Very Long Baseline Interferometry (VLBI) and the Navigation Technology Satellite (NTS) were compared using both methods to synchronize the Cesium clocks at the NASA Deep Space Net complexes at Madrid, Spain and Goldstone, California. Verification of the accuracy of both systems was examined. The VLBI experiments used the Wideband VLBI Data Acquisition System developed at the NASA Jet Propulsion Laboratory. The NTS Satellites were designed and built by the Naval Research Laboratory used with NTS Timing Receivers developed by the Goddard Space Flight Center. The two methods agreed at about the one-half microsecond level

Traveling waves of in vitro evolving RNA.

Populations of short self-replicating RNA variants have been confined to one side of a reaction-diffusion traveling wave front propagating along thin capillary tubes containing the Q beta viral enzyme. The propagation speed is accurately measurable with a magnitude of about 1 micron/sec, and the wave persists for hundreds of generations (of duration less than 1 min). Evolution of RNA occurs in the wavefront, as established by front velocity changes and gel electrophoresis of samples drawn from along the capillary. The high population numbers (approximately equal to 10(11], their well-characterized biochemistry, their short generation time, and the constant conditions make the system ideal for evolution experiments. Growth is monitored continuously by excitation of an added RNA-sensitive fluorescent dye, ethidium bromide. An analytic expression for the front velocity is derived for the multicomponent kinetic scheme that reduces, for a high RNA-enzyme binding constant, to the Fisher form v = 2 square root of kappa D, where D is the diffusion constant of the complex and kappa is the low-concentration overall replication rate coefficient. The latter is confirmed as the selective value-determining parameter by numerical solution of a two-species system

On-orbit frequency stability analysis of the GPS NAVSTAR-1 quartz clock and the NAVSTARs-6 and -8 rubidium clocks

An on-orbit frequency stability performance analysis of the GPS NAVSTAR-1 quartz clock and the NAVSTARs-6 and -8 rubidium clocks is presented. The clock offsets were obtained from measurements taken at the GPS monitor stations which use high performance cesium standards as a reference. Clock performance is characterized through the use of the Allan variance, which is evaluated for sample times of 15 minutes to two hours, and from one day to 10 days. The quartz and rubidium clocks' offsets were corrected for aging rate before computing the frequency stability. The effect of small errors in aging rate is presented for the NAVSTAR-8 rubidium clock's stability analysis. The analysis includes presentation of time and frequency residuals with respect to linear and quadratic models, which aid in obtaining aging rate values and identifying systematic and random effects. The frequency stability values were further processed with a time domain noise process analysis, which is used to classify random noise process and modulation type

Finite-size scaling of the error threshold transition in finite population

The error threshold transition in a stochastic (i.e. finite population) version of the quasispecies model of molecular evolution is studied using finite-size scaling. For the single-sharp-peak replication landscape, the deterministic model exhibits a first-order transition at $Q=Q_c=1/a$, where $Q$ is the probability of exact replication of a molecule of length $L \to \infty$, and $a$ is the selective advantage of the master string. For sufficiently large population size, $N$, we show that in the critical region the characteristic time for the vanishing of the master strings from the population is described very well by the scaling assumption \tau = N^{1/2} f_a \left [ \left (Q - Q_c) N^{1/2} \right ] , where $f_a$ is an $a$-dependent scaling function.Comment: 8 pages, 3 ps figures. submitted to J. Phys.

Anderson Localization, Non-linearity and Stable Genetic Diversity

In many models of genotypic evolution, the vector of genotype populations satisfies a system of linear ordinary differential equations. This system of equations models a competition between differential replication rates (fitness) and mutation. Mutation operates as a generalized diffusion process on genotype space. In the large time asymptotics, the replication term tends to produce a single dominant quasispecies, unless the mutation rate is too high, in which case the populations of different genotypes becomes de-localized. We introduce a more macroscopic picture of genotypic evolution wherein a random replication term in the linear model displays features analogous to Anderson localization. When coupled with non-linearities that limit the population of any given genotype, we obtain a model whose large time asymptotics display stable genotypic diversityComment: 25 pages, 8 Figure

Translocation of structured polynucleotides through nanopores

We investigate theoretically the translocation of structured RNA/DNA molecules through narrow pores which allow single but not double strands to pass. The unzipping of basepaired regions within the molecules presents significant kinetic barriers for the translocation process. We show that this circumstance may be exploited to determine the full basepairing pattern of polynucleotides, including RNA pseudoknots. The crucial requirement is that the translocation dynamics (i.e., the length of the translocated molecular segment) needs to be recorded as a function of time with a spatial resolution of a few nucleotides. This could be achieved, for instance, by applying a mechanical driving force for translocation and recording force-extension curves (FEC's) with a device such as an atomic force microscope or optical tweezers. Our analysis suggests that with this added spatial resolution, nanopores could be transformed into a powerful experimental tool to study the folding of nucleic acids.Comment: 9 pages, 5 figure